The first thing you should pay attention to is the currency rate which is typical for digital currencies as well as for fiat ones. Therefore, before exchanging BTC to USD, you should inquire about its value, and this can be done, for example, by monitoring the data on the Internet. Find up-to-date data at the current time and the rates and exchanges that you can use.
According to the elementary laws of economics, a transaction to buy currency should be made during the period of its price fall and sold during its rise. Therefore, if there is no urgency in the exchange, you should first of all be guided by this rule and wait for the appropriate BTC/USD rate.